C2orf72 information

C2orf72
Identifiers
Aliases	C2orf72, chromosome 2 open reading frame 72, Chromosome 2, Open Reading Frame 72
External IDs	MGI: 1920042; HomoloGene: 54780; GeneCards: C2orf72; OMA:C2orf72 - orthologs
Gene location (Human)
Chr.	Chromosome 2 (human)
End	231,049,719 bp
Gene location (Mouse)
Chr.	Chromosome 1 (mouse)
End	85,983,178 bp
RNA expression pattern
	Top expressed in
	right lobe of liver; ; right frontal lobe; ; nucleus accumbens; ; ventricular zone; ; amygdala; ; putamen; ; caudate nucleus; ; Brodmann area 9; ; hippocampus proper; ; cingulate gyrus;
	Top expressed in
	left lobe of liver; ; yolk sac; ; ventricular zone; ; Rostral migratory stream; ; left colon; ; epithelium of stomach; ; duodenum; ; medial ganglionic eminence; ; jejunum; ; substantia nigra;
	More reference expression data
	n/a
Orthologs
	257407
	72792
	ENSG00000204128
	ENSMUSG00000026227
	A6NCS6
	Q9CYS6
	NM_001144994
	NM_001144992; NM_001144993
	NP_001138466
	NP_001138464; NP_001138465
	Wikidata
View/Edit Human	View/Edit Mouse

C2orf72 (Chromosome 2, Open Reading Frame 72) is a gene in humans (Homo sapiens) that encodes a protein currently named after its gene, C2orf72.^[5] It is also designated LOC257407^[5] and can be found under GenBank accession code NM_001144994.2.^[6] The protein can be found under UniProt accession code A6NCS6.^[7]

This gene is primarily expressed in the liver, brain, placental, and small intestine tissues.^[8] C2orf72 is an intracellular protein that has been predicted to reside within the nucleus, cytosol, and plasma membrane of cells.^[5] The function of C2orf72 is unknown, but it is predicted to be involved in very-low-density lipoprotein particle assembly and also involved in the regulation of cholesterol esterification.^[9] This prediction also matches with the fact that both estradiol^[10] and testosterone^[11] have been reported to upregulate expression of C2orf72.^[12]

^ ^a ^b ^c GRCh38: Ensembl release 89: ENSG00000204128 – Ensembl, May 2017
^ ^a ^b ^c GRCm38: Ensembl release 89: ENSMUSG00000026227 – Ensembl, May 2017
^ "Human PubMed Reference:". National Center for Biotechnology Information, U.S. National Library of Medicine.
^ "Mouse PubMed Reference:". National Center for Biotechnology Information, U.S. National Library of Medicine.
^ ^a ^b ^c "C2orf72 GeneCards". www.genecards.org. Retrieved 2021-08-02.
^ Cite error: The named reference :1 was invoked but never defined (see the help page).
^ "iPTMnet Report A6NCS6 C2orf72". research.bioinformatics.udel.edu. Retrieved 2021-08-02.
^ Cite error: The named reference :7 was invoked but never defined (see the help page).
^ "ARCHS4". maayanlab.cloud. Retrieved 2021-08-02.
^ Cite error: The named reference :9 was invoked but never defined (see the help page).
^ Cite error: The named reference :10 was invoked but never defined (see the help page).
^ Cite error: The named reference :11 was invoked but never defined (see the help page).

[refGRCh38Ensembl-1] GRCh38: Ensembl release 89: ENSG00000204128 – Ensembl, May 2017

[refGRCm38Ensembl-2] GRCm38: Ensembl release 89: ENSMUSG00000026227 – Ensembl, May 2017

[3] "Human PubMed Reference:". National Center for Biotechnology Information, U.S. National Library of Medicine.

[4] "Mouse PubMed Reference:". National Center for Biotechnology Information, U.S. National Library of Medicine.

[:0-5] "C2orf72 GeneCards". www.genecards.org. Retrieved 2021-08-02.

[:1-6] Cite error: The named reference :1 was invoked but never defined (see the help page).

[:3-7] "iPTMnet Report A6NCS6 C2orf72". research.bioinformatics.udel.edu. Retrieved 2021-08-02.

[:7-8] Cite error: The named reference :7 was invoked but never defined (see the help page).

[:8-9] "ARCHS4". maayanlab.cloud. Retrieved 2021-08-02.

[:9-10] Cite error: The named reference :9 was invoked but never defined (see the help page).

[:10-11] Cite error: The named reference :10 was invoked but never defined (see the help page).

[:11-12] Cite error: The named reference :11 was invoked but never defined (see the help page).