C22orf31 information

C22orf31
Identifiers
Aliases	C22orf31, HS747E2A, bK747E2.1, chromosome 22 open reading frame 31
External IDs	HomoloGene: 81840; GeneCards: C22orf31; OMA:C22orf31 - orthologs
Gene location (Human)
Chr.	Chromosome 22 (human)
End	29,061,831 bp
RNA expression pattern
	Top expressed in
	testicle; ; pancreatic ductal cell; ; sperm; ; right testis; ; left testis; ; buccal mucosa cell; ; putamen; ; external globus pallidus; ; caudate nucleus; ; nucleus accumbens;
	n/a
	More reference expression data
	n/a
Orthologs
	25770
	n/a
	ENSG00000100249
	n/a
	O95567
	n/a
	NM_015370; NM_001386866
	n/a
	NP_056185
	n/a
	Wikidata
View/Edit Human

C22orf31 (chromosome 22, open reading frame 31) is a protein which in humans is encoded by the C22orf31 gene. The C22orf31 mRNA transcript has an upstream in-frame stop codon, while the protein has a domain of unknown function (DUF4662) spanning the majority of the protein-coding region.^[3] The protein has orthologs with high percent similarity in mammals.^[4] The most distant orthologs are found in species of bony fish, but C22orf31 is not found in any species of birds or amphibians.

Similar to many proteins, C22orf31 is found to be highly expressed in the testes. Analysis of in vivo mature oocytes has revealed increased levels of C22orf31^[5] while promoter analysis has identified transcription factors for C22orf31 that are active during myeloid cell differentiation.^[6]

^ ^a ^b ^c GRCh38: Ensembl release 89: ENSG00000100249 – Ensembl, May 2017
^ "Human PubMed Reference:". National Center for Biotechnology Information, U.S. National Library of Medicine.
^ "NCBI".
^ "NCBI Blastp".
^ "NCBI GEO Profile for record GDS3256, C22orf31". NCBI GEO.
^ Cite error: The named reference :2 was invoked but never defined (see the help page).

[refGRCh38Ensembl-1] GRCh38: Ensembl release 89: ENSG00000100249 – Ensembl, May 2017

[2] "Human PubMed Reference:". National Center for Biotechnology Information, U.S. National Library of Medicine.

[3] "NCBI".

[:0-4] "NCBI Blastp".

[:1-5] "NCBI GEO Profile for record GDS3256, C22orf31". NCBI GEO.

[:2-6] Cite error: The named reference :2 was invoked but never defined (see the help page).