C11orf54 information

C11orf54
Available structures
PDB	Ortholog search: PDBe RCSB
List of PDB id codes
	1XCR
Identifiers
Aliases	C11orf54, PTD012, PTOD012, chromosome 11 open reading frame 54
External IDs	OMIM: 615810; MGI: 1918234; HomoloGene: 8531; GeneCards: C11orf54; OMA:C11orf54 - orthologs
Gene location (Human)
Chr.	Chromosome 11 (human)
End	93,764,749 bp
Gene location (Mouse)
Chr.	Chromosome 9 (mouse)
End	15,217,744 bp
RNA expression pattern
	Top expressed in
	renal medulla; ; kidney; ; jejunal mucosa; ; liver; ; pancreatic epithelial cell; ; metanephros; ; retinal pigment epithelium; ; bronchial epithelial cell; ; gallbladder; ; right lobe of liver;
	Top expressed in
	parotid gland; ; kidney; ; brown adipose tissue; ; left lobe of liver; ; olfactory epithelium; ; jejunum; ; left colon; ; duodenum; ; intercostal muscle; ; white adipose tissue;
	More reference expression data
	n/a
Gene ontology
Molecular function	zinc ion binding; protein binding; hydrolase activity; hydrolase activity, acting on ester bonds; metal ion binding;
Cellular component	extracellular exosome; nucleus; nucleoplasm; nuclear body;
Biological process	metabolism;
	Sources:Amigo / QuickGO
Orthologs
	28970
	70984
	ENSG00000182919
	ENSMUSG00000031938
	Q9H0W9
	Q91V76
NM_001286067; NM_001286068; NM_001286069; NM_001286070; NM_001286071;
	NM_014039; NM_001351985; NM_001351986; NM_001351988; NM_001351989; NM_001351990; NM_001351991; NM_001351992; NM_001351993; NM_001351987; NM_001369406
	NM_001199484; NM_001199485; NM_133732; NM_001359258
NP_001272996; NP_001272997; NP_001272998; NP_001272999; NP_001273000;
	NP_054758; NP_001338914; NP_001338915; NP_001338916; NP_001338917; NP_001338918; NP_001338919; NP_001338920; NP_001338921; NP_001338922; NP_001356335
	NP_001186413; NP_001186414; NP_598493; NP_001346187
	Wikidata
View/Edit Human	View/Edit Mouse

Chromosome 11 open reading frame 54 (C11orf54) is a protein that in humans is encoded by the C11orf54 gene.^[5] The "Homo sapiens" gene, C11orf54 is also known as PTD012 and PTOD12. C11orf54 exhibits hydrolase activity on p-nitrophenyl acetate and acts on ester bonds, though the overall function is still not fully understood by the scientific community. The protein is highly conserved with the most distant homolog found is in bacteria.^[6]

^ ^a ^b ^c GRCh38: Ensembl release 89: ENSG00000182919 – Ensembl, May 2017
^ ^a ^b ^c GRCm38: Ensembl release 89: ENSMUSG00000031938 – Ensembl, May 2017
^ "Human PubMed Reference:". National Center for Biotechnology Information, U.S. National Library of Medicine.
^ "Mouse PubMed Reference:". National Center for Biotechnology Information, U.S. National Library of Medicine.
^ "Entrez Gene: C11orf54 chromosome 11 open reading frame 54".
^ "C11orf54". NCBI Gene. NCBI (National Center for Biotechnology Information).

[refGRCh38Ensembl-1] GRCh38: Ensembl release 89: ENSG00000182919 – Ensembl, May 2017

[refGRCm38Ensembl-2] GRCm38: Ensembl release 89: ENSMUSG00000031938 – Ensembl, May 2017

[3] "Human PubMed Reference:". National Center for Biotechnology Information, U.S. National Library of Medicine.

[4] "Mouse PubMed Reference:". National Center for Biotechnology Information, U.S. National Library of Medicine.

[entrez-5] "Entrez Gene: C11orf54 chromosome 11 open reading frame 54".

[NCBI_C11orf54-6] "C11orf54". NCBI Gene. NCBI (National Center for Biotechnology Information).