Diagnostic criteria for cerebral amyloid angiopathy
This article has multiple issues. Please help improve it or discuss these issues on the talk page. (Learn how and when to remove these template messages)
This article relies excessively on references to primary sources. Please improve this article by adding secondary or tertiary sources. Find sources: "Boston criteria" – news · newspapers · books · scholar · JSTOR(July 2023) (Learn how and when to remove this message)
This article is written like a personal reflection, personal essay, or argumentative essay that states a Wikipedia editor's personal feelings or presents an original argument about a topic. Please help improve it by rewriting it in an encyclopedic style.(October 2023) (Learn how and when to remove this message)
This article is an orphan, as no other articles link to it. Please introduce links to this page from related articles; try the Find link tool for suggestions. (May 2024)
(Learn how and when to remove this message)
The Boston criteria version 2.0[1] is a set of guidelines designed to diagnose cerebral amyloid angiopathy (CAA), a disease that affects small blood vessels in the brain, particularly those in the cortex and leptomeninges. Although the gold standard for diagnosis is histopathological examination, the Boston criteria provide clinicians with a probabilistic approach for diagnosis largely based on imaging characteristics.[2]
CAA is characterized by the progressive accumulation of a protein called amyloid β in the walls of these blood vessels. CAA is a major cause of lobar intracerebral haemorrhage, which is bleeding in the brain that occurs in the lobes of the brain. CAA is also a contributing factor to age-related cognitive impairment, which is a decline in cognitive function that occurs with aging.
It is important to accurately diagnose CAA during a patient's lifetime because it can affect clinical care and research participation.
Accurate diagnosis can also help researchers enroll appropriate participants in studies aimed at understanding the disease and developing new treatments.
The Boston criteria are intended to provide high diagnostic accuracy with reasonable simplicity, making them useful for both clinical practice and research. The criteria are designed to be applicable across the clinical spectrum of CAA-related presentations, meaning they can be used to diagnose the disease in patients with a variety of symptoms and conditions. The criteria are also intended to be used across clinical settings, meaning they can be applied in different healthcare environments and by different healthcare professionals.
In a study published in 2023, the authors found that the Boston criteria v2.0 substantially increases the proportion of patients with lobar ICH classified as probable CAA in comparison to the Boston criteria v1.5.[3]
^Charidimou, Andreas; Boulouis, Gregoire; Frosch, Matthew P; Baron, Jean-Claude; Pasi, Marco; Albucher, Jean Francois; Banerjee, Gargi; Barbato, Carmen; Bonneville, Fabrice; Brandner, Sebastian; Calviere, Lionel; Caparros, François; Casolla, Barbara; Cordonnier, Charlotte; Delisle, Marie-Bernadette (August 2022). "The Boston criteria version 2.0 for cerebral amyloid angiopathy: a multicentre, retrospective, MRI–neuropathology diagnostic accuracy study". The Lancet Neurology. 21 (8): 714–725. doi:10.1016/S1474-4422(22)00208-3. PMC 9389452. PMID 35841910.
^Schroeder, B. E.; Robertson, N. P.; Hughes, T. A. T. (2023-03-24). "Cerebral amyloid angiopathy: an update". Journal of Neurology. 270 (5): 2809–2811. doi:10.1007/s00415-023-11631-3. ISSN 0340-5354. PMC 10130108. PMID 36961527.
^Du, Yang; Zhang, Wenpeng; Locatelli, Martina; Simister, Robert J.; Jäger, H. Rolf; Werring, David J. (June 2023). "The Boston criteria version 2.0 increase the proportion of lobar intracerebral haemorrhage classified as probable cerebral amyloid angiopathy". Journal of Neurology. 270 (6): 3243–3245. doi:10.1007/s00415-023-11565-w. ISSN 1432-1459. PMID 36656357. S2CID 255973102.
The Bostoncriteria version 2.0 is a set of guidelines designed to diagnose cerebral amyloid angiopathy (CAA), a disease that affects small blood vessels...
available for biopsy, the BostonCriteria are used to determine probable CAA cases from MRI or CT scan data. The BostonCriteria require evidence of multiple...
cortex. Basal ganglia, posterior fossa, and brainstem are spared. Bostoncriteria is used to determine the likelihood of a cerebral hemorrhage due to...
Current Research. Boston, Massachusetts: Brill. ISBN 90-04-11142-5. Keith, Chris; Le Donne, Anthony, eds. (2012), Jesus, Criteria, and the Demise of...
chose to forgo the official criteria and retire Pedro Martínez' number 45. Martínez only spent seven of his 18 seasons in Boston. In justifying the number's...
There are a number of events held annually in Boston, Massachusetts, in the USA. They include: Culture in Boston Massachusetts culture Public holidays in the...
Millard criteria (Rule of 10) is a set of rules, which is to be fulfilled for undertaking elective surgery for children, and mostly used for reference...
urban core, plus surrounding developed areas that meet certain density criteria. Since urban areas are composed of census blocks and not cities, counties...
The Kocher criteria are a tool useful in the differentiation of septic arthritis from transient synovitis in the child with a painful hip. They are named...
tailwind, the Boston Marathon does not satisfy two of the criteria necessary for the ratification of world or American records. At the 2011 Boston Marathon...
and others, yet scientists have been unable to specify a set of clear criteria for empirically identifying these emotional events? What roles do language...
Boston Marathon qualifying standards allow runners to qualify for the Boston Marathon by running a previous marathon with a stipulated result within a...
paid on the achievement of specified revenue-based criteria through 2019. In January 2011, Boston acquired Atritech, Inc., for $100 million plus additional...
Players who do not meet the criteria for "international" players are automatically eligible if they meet any of the following criteria: They have no remaining...
about 25% it is a new mutation. Diagnosis is often based on the Ghent criteria, family history and genetic testing (DNA analysis). There is no known cure...
countryman Moses Mosop in 2:03:06. However, since the Boston course does not meet the criteria for record attempts, these times were not ratified by the...
receive additional points if they meet specific criteria, such as living in housing owned by the Boston Housing Authority, in the care of the Department...
The criteria for selection into the Hall is as follows: Player to be eligible for nomination must have played a minimum of three years with the Boston Red...
achievement or notoriety (most minor league players do not meet these criteria). Some notable players in the minor leagues may have their own profile...
continues through Item 60, unless certain discontinue criteria--or reverse-order administration criteria--are met. The patient is shown target stimuli and...
normal criteria of expensive production and famous stars." Scripter Stefan Petrucha and artist Kirk Van Wormer created the graphic novel Boston Blackie...
New England Law | Boston (formerly New England School of Law) is a private law school in Boston, Massachusetts. It was founded as Portia School of Law...
is being used in the clinical practice released in the year 1994 by the Criteria Committee of the American Heart Association, New York City Affiliate. Another...
received the No. 1 pick, the Los Angeles Lakers kept the No. 2 pick, the Boston Celtics via the Brooklyn Nets got the No. 3 pick, and everyone else stayed...
Players who do not meet the criteria for "international" players are automatically eligible if they meet any of the following criteria: They have completed four...
Northeast megalopolis, also known as the Northeast Corridor, Acela Corridor, Boston–Washington corridor, BosWash, or BosNYWash, is the world's largest megalopolis...
Global Information
