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Bolaamphiphile information


Bolaamphiphiles (also known as bolaform surfactants, bolaphiles, or alpha-omega-type surfactants) are amphiphilic molecules that have hydrophilic groups at both ends of a sufficiently long hydrophobic hydrocarbon chain. Compared to single-headed amphiphiles, the introduction of a second head-group generally induces a higher solubility in water, an increase in the critical micelle concentration (cmc), and a decrease in aggregation number. The aggregate morphologies of bolaamphiphiles include spheres, cylinders, disks, and vesicles. Bolaamphiphiles are also known to form helical structures that can form monolayer microtubular self-assemblies.[1]

  1. ^ P/ Mosae Selvakumar et al, J. Mol. Struct. 919 (2009) 72-78

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Bolaamphiphile

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phospholipid molecules into a single molecule with two polar heads (a bolaamphiphile); this fusion may make their membranes more rigid and better able to...

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Zhou (1998). "A Voltage-Gated Ion Channel Based on a Bis-Macrocyclic Bolaamphiphile". Journal of the American Chemical Society. 120 (13): 2997–3003. doi:10...

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Nanoparticles for drug delivery to the brain

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Transporter Classification Database

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Channel-forming Polytheonamide B Family 1.D.34 The Channel-forming Oligoester Bolaamphiphiles 1.D.35 The Pore-forming cyclic Lipodepsipeptide Family 1.D.36 The Oligobornene...

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