Beth Stevens information

Beth Stevens
Beth Stevens
Born	1970 (age 53–54); Brockton, Massachusetts, U.S.
Nationality	American
Alma mater	Northeastern University (BS); University of Maryland (PhD); Stanford University School of Medicine;
Known for	Microglia and complement receptor-based synaptic pruning mechanisms
Spouse	Rob Graham
	Scientific career
Fields	Neuroscience; Neuroimmunology;
Institutions	Boston Children's Hospital; Harvard Medical School
Thesis	Activity-dependent regulation of Schwann cell development by extracellular ATP (2003)
Doctoral advisor	Roger W. Davenport; R. Douglas Fields;
Other academic advisors	Ben Barres
Notable students	Dorothy P. Schafer

Beth Stevens (born 1970) is an associate professor in the Department of Neurology at Harvard Medical School and the F. M. Kirby Neurobiology Center at Boston Children’s Hospital.^[1] She has helped to identify the role of microglia and complement proteins in the "pruning" or removal of synaptic cells during brain development, and has also determined that the impaired or abnormal microglial function could be responsible for diseases like autism, schizophrenia, and Alzheimer's.^[1]

In 2012, Stevens’s team published evidence that microglia 'eat' synapses, especially those that are weak and unused.^[2] These findings pinned down a new role for microglia in wiring the brain, indicating that adult neural circuitry is determined not only by nerve cells but also by the brain’s immune cells. This helped to explain how the brain, which starts out with a surplus of neurons, trims some of the excess neurons away. Neuron named the paper its most influential publication of 2012.^[3]^[4]

^ ^a ^b "Beth Stevens". MacArthur Foundation. Retrieved 2015-09-29.
^ Schafer, DP; Lehrman, EK; Kautzman, AG; Koyama, R; Mardinly, AR; Yamasaki, R; Ransohoff, RM; Greenberg, ME; Barres, BA; Stevens, B (2012). "Microglia Sculpt Postnatal Neural Circuits in an Activity and Complement-Dependent Manner". Neuron. 74 (4): 691–705. doi:10.1016/j.neuron.2012.03.026. PMC 3528177. PMID 22632727.
^ "Neuron Highlights Stevens Lab Publication in 25th Anniversary Issue". Stevens Lab. 2013-10-31. Archived from the original on 2018-08-13. Retrieved 2018-03-02.
^ "Looking Back: Microglia in synaptic pruning". Cell. Retrieved 2015-10-14.^{[dead link]}

[MacArthur_Foundation-1] "Beth Stevens". MacArthur Foundation. Retrieved 2015-09-29.

[Neuron-2] Schafer, DP; Lehrman, EK; Kautzman, AG; Koyama, R; Mardinly, AR; Yamasaki, R; Ransohoff, RM; Greenberg, ME; Barres, BA; Stevens, B (2012). "Microglia Sculpt Postnatal Neural Circuits in an Activity and Complement-Dependent Manner". Neuron. 74 (4): 691–705. doi:10.1016/j.neuron.2012.03.026. PMC 3528177. PMID 22632727.

[Stevens_Lab_News-3] "Neuron Highlights Stevens Lab Publication in 25th Anniversary Issue". Stevens Lab. 2013-10-31. Archived from the original on 2018-08-13. Retrieved 2018-03-02.

[4] "Looking Back: Microglia in synaptic pruning". Cell. Retrieved 2015-10-14.^{[dead link]}

Beth Stevens information

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Beth Stevens
Born	1970 (age 53–54) Brockton, Massachusetts, U.S.
Nationality	American
Alma mater	Northeastern University (BS) University of Maryland (PhD) Stanford University School of Medicine
Known for	Microglia and complement receptor-based synaptic pruning mechanisms
Spouse	Rob Graham
Scientific career
Fields	Neuroscience Neuroimmunology
Institutions	Boston Children's Hospital Harvard Medical School
Thesis	Activity-dependent regulation of Schwann cell development by extracellular ATP (2003)
Doctoral advisor	Roger W. Davenport R. Douglas Fields
Other academic advisors	Ben Barres
Notable students	Dorothy P. Schafer