The Bile/Arsenite/Riboflavin Transporter (BART) superfamily is a superfamily of ubiquitous transport proteins. As of early 2016, the superfamily contains seven established families.[1] Functional data for members of all of these families are available.[1] The seven families are in the Transporter Classification Database with the following TC numbers, names and abbreviations include:[2]
TC# 2.A.10 - The 2-Keto-3-Deoxygluconate Transporter (KdgT) Family
TC# 2.A.28 - The Bile Acid:Na+ Symporter (BASS) Family
TC# 2.A.59 - The Arsenical Resistance-3 (ACR3) Family
TC# 2.A.69 - The Auxin Efflux Carrier (AEC) Family
TC# 2.A.87 - The Prokaryotic Riboflavin Transporter (P-RFT) Family
TC# 9.B.33 - The Sensor Histidine Kinase (SHK) Family
TC# 9.B.34 - The Kinase/Phosphatase/Cyclic-GMP Synthase/Cyclic di-GMP Hydrolase (KPSH) Family
The first identified substrates for the transporters within the first 5 families are indicated by the names of the families, but all of these families transport a variety of other substrates. The majority of the protein members of the first four of these families exhibit a probable 10 transmembrane spanner (TMS) topology that arose from a tandemly duplicated 5 TMS unit. The N- and C-termini are believed to be in the cytoplasm of bacterial cells, and the same may be true of most other members as well. Members of the RFT family have a 5 TMS topology, and are homologous to each of the two repeat units in the 10 TMS proteins. The other two families [sensor histidine kinase (SHK) and kinase/phosphatase/synthetase/hydrolase (KPSH)] have a single 5 TMS unit preceded by an N-terminal TMS and followed by a hydrophilic sensor histidine kinase domain (the SHK family) or catalytic domains resembling sensor kinase, phosphatase, cyclic di-guanylate (GMP) synthetase and cyclic di-GMP hydrolase catalytic domains, as well as various non-catalytic domains (the KPSH family). Because functional data are not available for the transmembrane domains of members of the SHK and KPSH families, it is not known if these transporter-like domains retain transport activity or have evolved exclusive functions in molecular reception and signal transmission. They could serve merely to anchor the catalytic domains to the membrane. Please refer to TCDB for more details.[1][2][3]
^ abcMansour, N.M., Sawhney, M., Tamang, D.G., Vogl, C., Saier, M.H. Jr. 2007. The bile-arsenite-riboflavin transporter (BART) superfamily FEBS Journal 274(3):612-29.
^Chen, J.S., V. Reddy, J.H. Chen, M.A. Shlykov, W.H. Zheng, J. Cho, M.R. Yen, and M.H. Saier, Jr. (2011). Phylogenetic characterization of transport protein superfamilies: superiority of SuperfamilyTree programs over those based on multiple alignments. J. Mol. Microbiol. Biotechnol. 21: 83-96.
Bile/Arsenite/Riboflavin Transporter (BART) superfamily is a superfamily of ubiquitous transport proteins. As of early 2016, the superfamily contains seven established...
arsenical resistance-3 (ACR3) family (TC# 2.A.59) is a member of the BARTsuperfamily. Based on operon analyses, ARC3 homologues may function either as secondary...
training rats to detect land mines was conceived of and developed by Belgian Bart Weetjens. Training starts at four weeks of age, when the rats are handled...
pseudonajatoxin a and pseudonajatoxin b. These are three-finger toxins, a superfamily of proteins found in the venom of many elapid snakes and responsible...
DMJ-021, was found in Converse County, Wyoming in 1986 by Brandon Flyr and Bart Lesco while out hiking and was reported to the people who owned the land...
be an apatosaurine, while others regard it as a basal member of the superfamily Diplodocoidea. Diplodocid fossils are found in North America, Europe...
Portuguese). Rio de Janeiro: Technical Books. ISBN 978-85-61368-00-5. De Boer, Bart A. (1993). Our Birds. Willemstad: Stichting Dierenbescherming Curaçao....
anemia-inducing feline leukemia virus subgroup C is a member of a transporter superfamily". J. Virol. 73 (8): 6500–5. doi:10.1128/JVI.73.8.6500-6505.1999. PMC 112732...
Rottier, Peter J. M.; Osterhaus, Albert D. M. E.; Bosch, Berend Jan; Haagmans, Bart L. (March 2013). "Dipeptidyl peptidase 4 is a functional receptor for the...
Poeciliidae). Evolution 32:320-333. Furness, Andrew I.; Avise, John C.; Pollux, Bart J.A.; Reynoso, Yuridia; Reznick, David N. (May 2021). "The evolution of the...
11464/diatom.31.1. Hannah Vossel; Jane M. Reed; Václav Houk; Aleksandra Cvetkoska; Bart Van de Vijver (2015). "Cyclotella paleo-ocellata, a new centric diatom (Bacillariophyta)...
Gerard M.; Roelants, Kim; O'Bryan, Moira K. (2008-12-01). "The CAP superfamily: cysteine-rich secretory proteins, antigen 5, and pathogenesis-related...
The 100K Pathogen Genome Project was launched in July 2012 by Bart Weimer (UC Davis) as an academic, public, and private partnership. It aims to sequence...
treated as a subspecies of Mythimna pallens, the common wainscot. S. favicolor Bart. Forewing pale olive brown ; veins concolorous, slightly defined by brown ;...
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transmission, and focuses on two classes of ion channels in the nicotinic superfamily, nicotinic and glycine receptors. Professor Sivilotti graduated in Pharmaceutical...
three remarkable new genera of Microlepidoptera. Sir George F. Hampson , Bart, B.A". Transactions of the Royal Entomological Society of London. 53 (2):...
Retrieved 11 July 2020. "08852 Pechipogo strigilata (Linnaeus, 1758) - Bart-Spannereule". Lepiforum e. V. Retrieved 11 July 2020. (in German) "Baardsnuituil...
1080/08912963.2016.1188385. S2CID 133166493. Michael Buckley; Stacey Warwood; Bart van Dongen; Andrew C. Kitchener; Phillip L. Manning (2017). "A fossil protein...