BAG1 information

BAG1
Available structures
PDB	Ortholog search: PDBe RCSB
List of PDB id codes
	1HX1, 1WXV, 3FZF, 3FZH, 3FZK, 3FZL, 3FZM, 3LDQ, 3M3Z
Identifiers
Aliases	BAG1, BAG-1, HAP, RAP46, BCL2 associated athanogene 1, BAG cochaperone 1
External IDs	OMIM: 601497; MGI: 108047; HomoloGene: 3190; GeneCards: BAG1; OMA:BAG1 - orthologs
Gene location (Human)
Chr.	Chromosome 9 (human)
End	33,264,720 bp
Gene location (Mouse)
Chr.	Chromosome 4 (mouse)
End	40,948,294 bp
RNA expression pattern
	Top expressed in
	palpebral conjunctiva; ; sperm; ; apex of heart; ; olfactory zone of nasal mucosa; ; right auricle; ; right testis; ; left testis; ; skin of abdomen; ; gastrocnemius muscle; ; skin of leg;
	Top expressed in
	seminiferous tubule; ; epithelium of stomach; ; lacrimal gland; ; crypt of lieberkuhn of small intestine; ; blood; ; mucous cell of stomach; ; decidua; ; right kidney; ; muscle of thigh; ; parotid gland;
	More reference expression data
	; ;
	More reference expression data
Gene ontology
Molecular function	chaperone binding; protein binding; adenyl-nucleotide exchange factor activity; ubiquitin protein ligase binding;
Cellular component	cytoplasm; cytosol; nucleus;
Biological process	regulation of cellular response to heat; cell surface receptor signaling pathway; negative regulation of apoptotic process; apoptotic process; regulation of catalytic activity; chaperone cofactor-dependent protein refolding;
	Sources:Amigo / QuickGO
Orthologs
	573
	12017
	ENSG00000107262
	ENSMUSG00000028416
	Q99933
	Q60739
	NM_004323; NM_001172415; NM_001349286; NM_001349299
	NM_001171739; NM_009736
	NP_001165886; NP_004314; NP_001336215; NP_001336228
	NP_001165210; NP_033866
	Wikidata
View/Edit Human	View/Edit Mouse

BAG family molecular chaperone regulator 1 is a protein that in humans is encoded by the BAG1 gene.^[5]

^ ^a ^b ^c GRCh38: Ensembl release 89: ENSG00000107262 – Ensembl, May 2017
^ ^a ^b ^c GRCm38: Ensembl release 89: ENSMUSG00000028416 – Ensembl, May 2017
^ "Human PubMed Reference:". National Center for Biotechnology Information, U.S. National Library of Medicine.
^ "Mouse PubMed Reference:". National Center for Biotechnology Information, U.S. National Library of Medicine.
^ Takayama S, Sato T, Krajewski S, Kochel K, Irie S, Millan JA, Reed JC (March 1995). "Cloning and functional analysis of BAG-1: a novel Bcl-2-binding protein with anti-cell death activity". Cell. 80 (2): 279–84. doi:10.1016/0092-8674(95)90410-7. PMID 7834747. S2CID 17824475.

[refGRCh38Ensembl-1] GRCh38: Ensembl release 89: ENSG00000107262 – Ensembl, May 2017

[refGRCm38Ensembl-2] GRCm38: Ensembl release 89: ENSMUSG00000028416 – Ensembl, May 2017

[3] "Human PubMed Reference:". National Center for Biotechnology Information, U.S. National Library of Medicine.

[4] "Mouse PubMed Reference:". National Center for Biotechnology Information, U.S. National Library of Medicine.

[pmid7834747-5] Takayama S, Sato T, Krajewski S, Kochel K, Irie S, Millan JA, Reed JC (March 1995). "Cloning and functional analysis of BAG-1: a novel Bcl-2-binding protein with anti-cell death activity". Cell. 80 (2): 279–84. doi:10.1016/0092-8674(95)90410-7. PMID 7834747. S2CID 17824475.

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