Global InformationAureusidin synthase information
| Aureusidin synthase | |||||||||
|---|---|---|---|---|---|---|---|---|---|
| Identifiers | |||||||||
| EC no. | 1.21.3.6 | ||||||||
| CAS no. | 320784-48-3 | ||||||||
| Databases | |||||||||
| IntEnz | IntEnz view | ||||||||
| BRENDA | BRENDA entry | ||||||||
| ExPASy | NiceZyme view | ||||||||
| KEGG | KEGG entry | ||||||||
| MetaCyc | metabolic pathway | ||||||||
| PRIAM | profile | ||||||||
| PDB structures | RCSB PDB PDBe PDBsum | ||||||||
| |||||||||
Aureusidin synthase (EC 1.21.3.6, AmAS1) is an enzyme with systematic name 2',4,4',6'-tetrahydroxychalcone 4'-O-beta-D-glucoside:oxygen oxidoreductase.[1][2][3][4]
Aureusidin synthase has two main enzymatic tasks: hydroxylation at the 3-position on the B-ring of chalcones, and the oxidative cyclization of chalcones to form aurones.[2] The chalcones modified are typically glucosylated 2',4,4',6'-tetrahydroxychalcone (THC) and 2',3,4,4',6'-pentahydroxychalcone (PHC).[2] These aurones, particularly auresidin, form pigments for coloration in flowers.[1] These pigments may have been developed to attract and guide bees for pollination,[5] but they also provide protection from viruses, pests and fungus.[6]
- ^ a b Nakayama T, Yonekura-Sakakibara K, Sato T, Kikuchi S, Fukui Y, Fukuchi-Mizutani M, Ueda T, Nakao M, Tanaka Y, Kusumi T, Nishino T (November 2000). "Aureusidin synthase: a polyphenol oxidase homolog responsible for flower coloration". Science. 290 (5494): 1163–6. Bibcode:2000Sci...290.1163N. doi:10.1126/science.290.5494.1163. PMID 11073455.
- ^ a b c Nakayama T, Sato T, Fukui Y, Yonekura-Sakakibara K, Hayashi H, Tanaka Y, Kusumi T, Nishino T (June 2001). "Specificity analysis and mechanism of aurone synthesis catalyzed by aureusidin synthase, a polyphenol oxidase homolog responsible for flower coloration". FEBS Letters. 499 (1–2): 107–11. doi:10.1016/S0014-5793(01)02529-7. PMID 11418122.
- ^ Sato T, Nakayama T, Kikuchi S, Fukui Y, Yonekura-Sakakibara K, Ueda T, Nishino T, Tanaka Y, Kusumi T (January 2001). "Enzymatic formation of aurones in the extracts of yellow snapdragon flowers". Plant Science. 160 (2): 229–236. doi:10.1016/s0168-9452(00)00385-x. PMID 11164594.
- ^ Ono E, Fukuchi-Mizutani M, Nakamura N, Fukui Y, Yonekura-Sakakibara K, Yamaguchi M, Nakayama T, Tanaka T, Kusumi T, Tanaka Y (July 2006). "Yellow flowers generated by expression of the aurone biosynthetic pathway". Proceedings of the National Academy of Sciences of the United States of America. 103 (29): 11075–80. Bibcode:2006PNAS..10311075O. doi:10.1073/pnas.0604246103. PMC 1544175. PMID 16832053.
- ^ Lunau K, Wacht S, Chittka L (1996). "Colour choices of naive bumble bees and their implications for colour perception". Journal of Comparative Physiology A. 178 (4). doi:10.1007/BF00190178. S2CID 21435915.
- ^ Boumendjel A (December 2003). "Aurones: a subclass of flavones with promising biological potential". Current Medicinal Chemistry. 10 (23): 2621–30. doi:10.2174/0929867033456468. PMID 14529476.