Atrolysin F (EC 3.4.24.45, Crotalus atrox metalloendopeptidase, hemorrhagic toxin f, Crotalus atrox metalloendopeptidase f) is an enzyme.[1] This enzyme catalyses the following chemical reaction
Cleavage of Val2-Asn, Gln4-His, Leu6-Cys, His10-Leu, Ala14-Leu and Tyr16-Leu bonds in insulin B chain
This endopeptidase is present in the venom of the western diamondback rattlesnake (Crotalus atrox).
^Nikai T, Mori N, Kishida M, Sugihara H, Tu AT (June 1984). "Isolation and biochemical characterization of hemorrhagic toxin f from the venom of Crotalus atrox (western diamondback rattlesnake)". Archives of Biochemistry and Biophysics. 231 (2): 309–19. doi:10.1016/0003-9861(84)90393-x. PMID 6375570.
as arthritis, and tumor metastasis as well. Atrolysin B Atrolysin C Atrolysin D Atrolysin E AtrolysinF Bjarnason JB, Tu AT (August 1978). "Hemorrhagic...
to a disintegrin domain. Such is the case for trimerelysin I (HR1B), atrolysin E (Ht-e) and trigramin. It has been suggested that these proteinases are...