Angelicin synthase (EC 1.14.13.115, CYP71AJ4 (gene)) is an enzyme with systematic name (+)-columbianetin,NADPH:oxygen oxidoreductase.[1] This enzyme catalyses the following chemical reaction:
Angelicin synthase is a P450 monooxygenase enzyme.
^Larbat R, Hehn A, Hans J, Schneider S, Jugdé H, Schneider B, Matern U, Bourgaud F (February 2009). "Isolation and functional characterization of CYP71AJ4 encoding for the first P450 monooxygenase of angular furanocoumarin biosynthesis". The Journal of Biological Chemistry. 284 (8): 4776–85. doi:10.1074/jbc.M807351200. PMID 19098286.
Angelicinsynthase (EC 1.14.13.115, CYP71AJ4 (gene)) is an enzyme with systematic name (+)-columbianetin,NADPH:oxygen oxidoreductase. This enzyme catalyses...
terminated with the oxidation of (+)-columbianetin yielding angelicin by angelicinsynthase (AS) which is also considered as the enzyme of cytochrome P450...
furanocoumarins can be regarded as derivatives of either psoralen or angelicin. Psoralen and its derivatives are often referred to as the linear furanocoumarins...