Global InformationAmyoplasia information
Amyoplasia is a condition characterized by a generalized lack in the newborn of muscular development and growth, with contracture and deformity that affect at least two joints.[1] It is the most common form of arthrogryposis.[2]
It is characterized by the four limbs being involved, and by the replacement of skeletal muscle by dense fibrous and adipose tissue.[3] Studies involving amyoplasia have revealed similar findings of the muscle tissue due to various causes including that seen in sacral agenesis and amyotrophic lateral sclerosis. So amyoplasia may also include an intermediate common pathway, rather than the primary cause of the contractors.
- ^ Cite error: The named reference
pmid33321243was invoked but never defined (see the help page). - ^ Jill M. Sells; Kenneth M. Jaffe; Judith G. Hall (1 February 1996). "Amyoplasia, the Most Common Type of Arthrogryposis: The Potential for Good Outcome". Pediatrics. 97 (2): 225–231. doi:10.1542/peds.97.2.225. PMID 8584382. S2CID 245176731.
- ^ Bernstein, RM (2002). "Arthrogryposis and amyoplasia". The Journal of the American Academy of Orthopaedic Surgeons. 10 (6): 417–24. doi:10.5435/00124635-200211000-00006. PMID 12470044. S2CID 36302153.