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Ambazone information


Ambazone[1]
Names
IUPAC name
[4-(2-(Diaminomethylidene)hydrazinyl)phenyl]iminothiourea
Other names
2-[4-[(aminoiminomethyl)hydrazono]-2,5-cyclohexadien-1-ylidene]-Hydrazinecarbothioamide; (4-Oxo-2,5-cyclohexadien-1-ylideneamino)guanidine thiosemicarbazone; 1,4-Benzoquinone amidinohydrazone thiosemicarbazone; Ambazon; Anginon; Benzoquinone guanylhydrazone thiosemicarbazone; Faringosept; Guanothiazon; Inversal; Inversal; Ivertol; N-Guanidino-N'-thioureido-p-benzoquinonediimide; Primal; p-Benzoquinone amidinohydrazone thiosemicarbazone;Faringosept (TN); Ambazone (INN); OAMBAZONE; Ambazonum [INN-Latin]; Ambazona [INN-Spanish]; Ambazone [INN:BAN:DCF]; CCRIS 1926; MLS001240207
Identifiers
CAS Number
  • 539-21-9 checkY
3D model (JSmol)
  • Interactive image
ChEMBL
  • ChEMBL2103762 ☒N
ChemSpider
  • 12232507 checkY
ECHA InfoCard 100.007.922 Edit this at Wikidata
EC Number
  • 208-713-0
KEGG
  • D07376 checkY
PubChem CID
  • 1549158
UNII
  • BYK4592A3Q checkY
CompTox Dashboard (EPA)
  • DTXSID3046407 Edit this at Wikidata
InChI
  • InChI=1S/C8H11N7S/c9-7(10)14-12-5-1-3-6(4-2-5)13-15-8(11)16/h1-4H,(H4,9,10,14)(H3,11,15,16)/b12-5-,13-6+ checkY
    Key: MLMFUKWWZIZRHX-UWRPRBHNSA-N checkY
  • InChI=1/C8H11N7S/c9-7(10)14-12-5-1-3-6(4-2-5)13-15-8(11)16/h1-4H,(H4,9,10,14)(H3,11,15,16)/b12-5-,13-6+
    Key: MLMFUKWWZIZRHX-UWRPRBHNBF
SMILES
  • NC(=S)N\N=C1\C=C/C(=N\NC(N)=N)/C=C1
Properties
Chemical formula
 C8H11N7S
Molar mass 237.28 g/mol
Appearance Dark Brown Powder
Solubility in water
 0.2 mg/100 ml water
Pharmacology
ATC code
 R02AA01 (WHO)
Except where otherwise noted, data are given for materials in their standard state (at 25 °C [77 °F], 100 kPa).
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Infobox references

Ambazone is an oral antiseptic.

Ambazone was patented in 1957 by Bayer under the trade name Iversal, and briefly used in Germany. It is still used in Russia, countries of the former Soviet Union, Poland[2] and Romania. It has not been approved by the United States Food and Drug Administration (FDA).[citation needed]

  1. ^ Ambazone
  2. ^ "Faringosept tabletki - działanie, dawkowanie, cena, refundacja | Medycyna Praktyczna".

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