Agglomerin information

Agglomerin A
Names
	Preferred IUPAC name 3-Decanoyl-4-hydroxy-5-methylidenefuran-2(5H)-one
	Other names 3-[(Z)-1-hydroxydecylidene]-5-methylenetetrahydrofuran-2,4-dione
Identifiers
CAS Number	125620-70-4;
3D model (JSmol)	Interactive image;
ChEMBL	ChEMBL301568;
ChemSpider	19982638;
PubChem CID	54697845;
CompTox Dashboard (EPA)	DTXSID90154804 ;
	InChI InChI=1S/C15H22O4/c1-3-4-5-6-7-8-9-10-12(16)13-14(17)11(2)19-15(13)18/h17H,2-10H2,1H3 Key: YFNGFFUIVKWQHE-UHFFFAOYSA-N;
	SMILES O=C(C1=C(O)C(OC1=O)=C)CCCCCCCCC;
Properties
Chemical formula	C15H22O4
Molar mass	266.34 g/mol
Appearance	Colorless crystalline powders (Na salt)
Melting point	113-115 (A), 85-88 (B), 125-128 (C), 103-106 (D)
Solubility in water	Insoluble (Na salt)
	Except where otherwise noted, data are given for materials in their standard state (at 25 °C [77 °F], 100 kPa). Infobox references

Agglomerins are bacterial natural products, identified as metabolites of Pantoea agglomerans which was isolated in 1989 from river water in Kobe, Japan.^[1] They belong to the class of tetronate antibiotics, which include tetronomycin, tetronasin, and abyssomicin C. The members of the agglomerins differ only in the composition of the acyl chain attached to the tetronate ring. They possess antibiotic activity against anaerobic bacteria and weak activity against aerobic bacteria in vitro. The structures were solved in 1990.^[2] Agglomerin A is the major component (38%), followed by agglomerin B (30%), agglomerin C (24%), and agglomerin D (8%).^[3]

^ Shoji, Jun'Ichi; Sakazaki, Ryuji; Hattori, Teruo; Matsumoto, Koichi; Uotani, Nobuo; Yoshida, Tadashi (1989). "Isolation and characterization of agglomerinsA, B, C and D." The Journal of Antibiotics. 42 (12): 1729–1733. doi:10.7164/antibiotics.42.1729. ISSN 0021-8820. PMID 2621155.
^ Terui, Yoshihiro; Sakazaki, Ryuji; Shoji, Jun'Ichi (1990). "Structures of agglomerins". The Journal of Antibiotics. 43 (10): 1245–1253. doi:10.7164/antibiotics.43.1245. ISSN 0021-8820. PMID 2258324.
^ Microbiology Abstracts: Bacteriology. Information Retrieval. 1990.

[1] Shoji, Jun'Ichi; Sakazaki, Ryuji; Hattori, Teruo; Matsumoto, Koichi; Uotani, Nobuo; Yoshida, Tadashi (1989). "Isolation and characterization of agglomerinsA, B, C and D." The Journal of Antibiotics. 42 (12): 1729–1733. doi:10.7164/antibiotics.42.1729. ISSN 0021-8820. PMID 2621155.

[2] Terui, Yoshihiro; Sakazaki, Ryuji; Shoji, Jun'Ichi (1990). "Structures of agglomerins". The Journal of Antibiotics. 43 (10): 1245–1253. doi:10.7164/antibiotics.43.1245. ISSN 0021-8820. PMID 2258324.

[3] Microbiology Abstracts: Bacteriology. Information Retrieval. 1990.