Global Information Lookup Global Information

ARMET information


MANF
Available structures
PDBOrtholog search: PDBe RCSB
Identifiers
AliasesMANF, ARMET, ARP, arginine-rich, mutated in early-stage tumors, arginine-rich protein, mesencephalic astrocyte-derived neurotrophic factor, mesencephalic astrocyte derived neurotrophic factor
External IDsOMIM: 601916 MGI: 1922090 HomoloGene: 4383 GeneCards: MANF
Orthologs
SpeciesHumanMouse
Entrez
Ensembl
UniProt
RefSeq (mRNA)

NM_006010

NM_029103

RefSeq (protein)

NP_006001

n/a

Location (UCSC)Chr 3: 51.39 – 51.39 Mbn/a
PubMed search[2][3]
Wikidata
View/Edit HumanView/Edit Mouse

Arginine-rich, mutated in early-stage tumors (ARMET), arginine-rich protein (ARP), or mesencephalic astrocyte-derived neurotrophic factor (MANF) is a protein that in humans is encoded by the MANF housekeeping gene.[4][5]

This gene encodes a highly conserved protein whose function is known. The protein was initially thought to be longer at the N-terminus and to contain an arginine-rich region but transcribed evidence indicates a smaller open reading frame that does not encode the arginine tract. The presence of a specific mutation changing the previously numbered codon 50 from ATG to AGG, or deletion of that codon, has been reported in a variety of solid tumors. With the protein size correction, this codon is now identified as the initiation codon.[5]

  1. ^ a b c GRCh38: Ensembl release 89: ENSG00000145050 – Ensembl, May 2017
  2. ^ "Human PubMed Reference:". National Center for Biotechnology Information, U.S. National Library of Medicine.
  3. ^ "Mouse PubMed Reference:". National Center for Biotechnology Information, U.S. National Library of Medicine.
  4. ^ Petrova P, Raibekas A, Pevsner J, Vigo N, Anafi M, Moore MK, Peaire AE, Shridhar V, Smith DI, Kelly J, Durocher Y, Commissiong JW (Jun 2003). "MANF: a new mesencephalic, astrocyte-derived neurotrophic factor with selectivity for dopaminergic neurons". J Mol Neurosci. 20 (2): 173–88. doi:10.1385/JMN:20:2:173. PMID 12794311. S2CID 218459504.
  5. ^ a b "Entrez Gene: ARMET arginine-rich, mutated in early stage tumors".

and 24 Related for: ARMET information

Request time (Page generated in 0.5525 seconds.)

Armet

Last Update:

The armet is a type of combat helmet which was developed in the 15th century. It was extensively used in Italy, France, England, the Low Countries and...

Word Count : 916

ARMET

Last Update:

Arginine-rich, mutated in early-stage tumors (ARMET), arginine-rich protein (ARP), or mesencephalic astrocyte-derived neurotrophic factor (MANF) is a...

Word Count : 554

Terradyne Armored Vehicles Gurkha

Last Update:

sharing the same engine and interior. The Gurkha was developed in 2005 by Armet Armored Vehicles. In 2011, the Gurkha vehicle design was purchased by Terradyne...

Word Count : 830

Louis Armet

Last Update:

Louis Logue Armét (/ɑːrˈmeɪ/ ar-MAY; October 26, 1914 – October 11, 1981) was an American architect and strong proponent of Googie architecture during...

Word Count : 169

Armet Davis Newlove Architects

Last Update:

Armet Davis Newlove Architects, formerly Armét & Davis, is a Californian architectural firm known for working in the Googie architecture style that marks...

Word Count : 1083

Armet Armored Vehicles

Last Update:

Armet Armored Vehicles is a defunct vehicle manufacturer founded and formerly headquartered in King City, Ontario with US operations in Danville, Virginia...

Word Count : 278

Close helmet

Last Update:

the superficially similar armet in the late 15th century. In contemporary sources it was sometimes also referred to as an 'armet', though modern scholarship...

Word Count : 721

Googie architecture

Last Update:

included John Lautner, Douglas Honnold, and the team of Louis Armet and Eldon Davis of Armet & Davis firm, which they founded in 1947. Also instrumental...

Word Count : 3592

Juan Armet

Last Update:

Juan Armet de Castellví, nicknamed "Kinké" (30 June 1895 in Terrassa – 5 October 1956 in Madrid) was a Spanish footballer who played as a forward, and...

Word Count : 493

Armet Francis

Last Update:

Armet Francis (born 29 January 1945) is a Jamaican-born photographer and publisher who has lived in London since the 1950s. He has been documenting and...

Word Count : 1262

Francisco Armet

Last Update:

Francisco Armet de Castellví (5 November 1892 in Terrassa – 23 March 1973 in Madrid), nicknamed "Pakán", was a Spanish footballer who played as a defender...

Word Count : 504

Sallet

Last Update:

and Hungary during the mid-15th century. In Italy, France and England the armet helmet was also popular, but in Germany the sallet became almost universal...

Word Count : 1106

The Corruption of Chris Miller

Last Update:

apart from Manuel Goyanes. Anabel Films founder and producer, actor Javier Armet, developed an original idea from Santiago Montcada to produce this high-budget...

Word Count : 1111

Horned helmet of Henry VIII

Last Update:

The horned helmet of Henry VIII (more properly called the parade armet) is the surviving part of a full suit of armour made by Konrad Seusenhofer between...

Word Count : 961

Emile Armet de Lisle

Last Update:

Emile Armet de Lisle (1853–1928) was a French industrialist and chemist who helped develop the French radium industry in the early 20th century. Around...

Word Count : 1499

Catalonia national football team

Last Update:

Catalan team was: Renyé, Amechazurra, Irízar, A. Massana, Sagnier, Quirante, Armet-Kinké, A. Comamala, C. Comamala, Janer and Forns. The Selection of foreigners...

Word Count : 2610

List of medieval armour components

Last Update:

very similar visually to an armet and often the two are confused. However, it lacks the hinged cheekplates of an armet and instead has a movable bevor...

Word Count : 196

Helmet

Last Update:

developments included the great helm, the bascinet, the frog-mouth helm, and the armet. The great seal of Owain Glyndŵr (c. 1359 – c. 1415) depicts the prince...

Word Count : 1222

Konrad Seusenhofer

Last Update:

with a suit of armour which included the most unusual ‘Horned helmet’ or armet, later chosen as the symbol of the Royal Armouries Museum in Leeds. Three...

Word Count : 181

Victoria Police Special Operations Group

Last Update:

funded by the Federal Government. The BearCat had replaced a Canadian made Armet Armored Vehicles Balkan Mk7 that had been in service since 2009. The Balkan...

Word Count : 1951

Gorget

Last Update:

lower face and throat with plate were paired with a separate bevor, and the armet was often fitted with a wrapper that included gorget lames protecting the...

Word Count : 2413

Funerary Helmets

Last Update:

or at jousts. A variety of helmets were used as shown below, such as the Armet, Bascinet, Great helm, etc. King Henry V (d. 1422), Westminster Abbey. Set...

Word Count : 816

Cheekpiece

Last Update:

of a bit for horses, e.g. the bit shank A part of body armor such as the armet This disambiguation page lists articles associated with the title Cheekpiece...

Word Count : 80

List of Real Madrid CF managers

Last Update:

Francisco Bru 1934 1941 118 71 13 34 290 152 060.17 2 Copa del Rey Juan Armet 1941 September 1943 46 23 7 16 96 72 050.00 Ramón Encinas September 1943...

Word Count : 414

PDF Search Engine © AllGlobal.net