Protein-coding gene in the species Homo sapiens
AGXT2 Identifiers Aliases AGXT2 , AGT2, DAIBAT, alanine--glyoxylate aminotransferase 2, BAIBAExternal IDs OMIM: 612471; MGI: 2146052; HomoloGene: 12887; GeneCards: AGXT2; OMA:AGXT2 - orthologs EC number 2.6.1.40 Gene location (Human) Chr. Chromosome 5 (human)[1] Band 5p13.2 Start 34,998,101 bp[1] End 35,048,135 bp[1]
Gene location (Mouse) Chr. Chromosome 15 (mouse)[2] Band 15|15 A1 Start 10,358,618 bp[2] End 10,410,239 bp[2]
RNA expression pattern Bgee Human Mouse (ortholog) Top expressed in right lobe of liver kidney renal medulla renal cortex jejunal mucosa gallbladder duodenum caput epididymis muscle tissue placenta
Top expressed in left lobe of liver kidney proximal tubule yolk sac islet of Langerhans ureter duodenum sexually immature organism adrenal gland jejunum
More reference expression data
BioGPS
Gene ontology Molecular function
transferase activity
(R)-3-amino-2-methylpropionate-pyruvate transaminase activity
pyridoxal phosphate binding
catalytic activity
alanine-glyoxylate transaminase activity
identical protein binding
transaminase activity Cellular component
mitochondrial matrix
mitochondrion Biological process
glycine biosynthetic process, by transamination of glyoxylate
positive regulation of nitric oxide biosynthetic process
glyoxylate catabolic process
L-alanine catabolic process, by transamination
glyoxylate metabolic process Sources:Amigo / QuickGO
Orthologs Species Human Mouse Entrez Ensembl UniProt RefSeq (mRNA) NM_001031851
RefSeq (protein) NP_001027021
Location (UCSC) Chr 5: 35 – 35.05 Mb Chr 15: 10.36 – 10.41 Mb PubMed search [3] [4]
Wikidata View/Edit Human View/Edit Mouse
The human AGXT2 gene encodes the protein Alanine—glyoxylate aminotransferase 2 .
[5]
^ a b c GRCh38: Ensembl release 89: ENSG00000113492 – Ensembl, May 2017
^ a b c GRCm38: Ensembl release 89: ENSMUSG00000089678 – Ensembl, May 2017
^ "Human PubMed Reference:". National Center for Biotechnology Information, U.S. National Library of Medicine . ^ "Mouse PubMed Reference:". National Center for Biotechnology Information, U.S. National Library of Medicine . ^
"Entrez Gene: Alanine--glyoxylate aminotransferase 2". Retrieved 2014-01-12 .
Global Information
