positive regulation of calcium ion transport into cytosol
positive regulation of inositol phosphate biosynthetic process
negative regulation of cell death
activation of phospholipase C activity
multicellular organism development
cell surface receptor signaling pathway
development of primary female sexual characteristics
spermatogenesis
response to ethanol
cAMP-mediated signaling
signal transduction
positive regulation of small GTPase mediated signal transduction
G protein-coupled receptor signaling pathway
positive regulation of cAMP-mediated signaling
Sources:Amigo / QuickGO
Orthologs
Species
Human
Mouse
Entrez
117
11517
Ensembl
ENSG00000078549
ENSMUSG00000029778
UniProt
P41586
P70205
RefSeq (mRNA)
NM_001118 NM_001199635 NM_001199636 NM_001199637
NM_001025372 NM_007407
RefSeq (protein)
NP_001109 NP_001186564 NP_001186565 NP_001186566
NP_001020543 NP_031433
Location (UCSC)
Chr 7: 31.05 – 31.11 Mb
Chr 6: 55.43 – 55.48 Mb
PubMed search
[3]
[4]
Wikidata
View/Edit Human
View/Edit Mouse
Pituitary adenylate cyclase-activating polypeptide type I receptor also known as PAC1, is a protein that in humans is encoded by the ADCYAP1R1 gene.[5] This receptor binds pituitary adenylate cyclase activating peptide.[6][7]
^ abcGRCh38: Ensembl release 89: ENSG00000078549 – Ensembl, May 2017
^ abcGRCm38: Ensembl release 89: ENSMUSG00000029778 – Ensembl, May 2017
^"Human PubMed Reference:". National Center for Biotechnology Information, U.S. National Library of Medicine.
^"Mouse PubMed Reference:". National Center for Biotechnology Information, U.S. National Library of Medicine.
^Cite error: The named reference entrez was invoked but never defined (see the help page).
^Ogi K, Miyamoto Y, Masuda Y, Habata Y, Hosoya M, Ohtaki T, Masuo Y, Onda H, Fujino M (Nov 1993). "Molecular cloning and functional expression of a cDNA encoding a human pituitary adenylate cyclase activating polypeptide receptor". Biochemical and Biophysical Research Communications. 196 (3): 1511–21. doi:10.1006/bbrc.1993.2423. PMID 7902709.
^Vaudry D, Gonzalez BJ, Basille M, Yon L, Fournier A, Vaudry H (Jun 2000). "Pituitary adenylate cyclase-activating polypeptide and its receptors: from structure to functions". Pharmacological Reviews. 52 (2): 269–324. PMID 10835102.
receptor also known as PAC1, is a protein that in humans is encoded by the ADCYAP1R1 gene. This receptor binds pituitary adenylate cyclase activating peptide...
neuroendocrine hormones. While the receptors for VIP (VIRP 1 and 2) and PACAP (ADCYAP1R1) share homology, they differ in their substrate specificities and expression...