ADAM33 information

ADAM33
Available structures
PDB	Ortholog search: PDBe RCSB
List of PDB id codes
	1R54, 1R55
Identifiers
Aliases	ADAM33, C20orf153, DJ964F7.1, ADAM metallopeptidase domain 33
External IDs	OMIM: 607114; MGI: 1341813; HomoloGene: 11881; GeneCards: ADAM33; OMA:ADAM33 - orthologs
Gene location (Human)
Chr.	Chromosome 20 (human)
End	3,682,246 bp
Gene location (Mouse)
Chr.	Chromosome 2 (mouse)
End	130,905,734 bp
RNA expression pattern
	Top expressed in
	canal of the cervix; ; body of uterus; ; left uterine tube; ; stromal cell of endometrium; ; muscle layer of sigmoid colon; ; ectocervix; ; gastric mucosa; ; Descending thoracic aorta; ; ascending aorta; ; myometrium;
	Top expressed in
	ascending aorta; ; aortic valve; ; lip; ; belly cord; ; sciatic nerve; ; dermis; ; tunica media of zone of aorta; ; muscle of thigh; ; embryo; ; superior frontal gyrus;
	More reference expression data
	n/a
Gene ontology
Molecular function	peptidase activity; metalloendopeptidase activity; protein binding; hydrolase activity; metallopeptidase activity; metal ion binding; zinc ion binding;
Cellular component	integral component of membrane; membrane;
Biological process	proteolysis;
	Sources:Amigo / QuickGO
Orthologs
	80332
	110751
	ENSG00000149451
	ENSMUSG00000027318
	Q9BZ11; Q08AM2
	Q923W9
	NM_001282447; NM_025220; NM_153202
	NM_001163529; NM_033615
	NP_001269376; NP_079496; NP_694882
	NP_001157001; NP_291093
	Wikidata
View/Edit Human	View/Edit Mouse

Disintegrin and metalloproteinase domain-containing protein 33 is an enzyme that in humans is encoded by the ADAM33 gene.^[5]^[6]

^ ^a ^b ^c GRCh38: Ensembl release 89: ENSG00000149451 – Ensembl, May 2017
^ ^a ^b ^c GRCm38: Ensembl release 89: ENSMUSG00000027318 – Ensembl, May 2017
^ "Human PubMed Reference:". National Center for Biotechnology Information, U.S. National Library of Medicine.
^ "Mouse PubMed Reference:". National Center for Biotechnology Information, U.S. National Library of Medicine.
^ Yoshinaka T, Nishii K, Yamada K, Sawada H, Nishiwaki E, Smith K, Yoshino K, Ishiguro H, Higashiyama S (January 2002). "Identification and characterization of novel mouse and human ADAM33s with potential metalloprotease activity". Gene. 282 (1–2): 227–36. doi:10.1016/S0378-1119(01)00818-6. PMID 11814695.
^ "Entrez Gene: ADAM33 ADAM metallopeptidase domain 33".

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