ADAM10 endopeptidase (EC 3.4.24.81, Kuzbanian protein, myelin-associated disintegrin metalloproteinase) is an enzyme.[1] This enzyme catalyses the following chemical reaction
Endopeptidase of broad specificity
This enzyme belongs to the peptidase family M12.
^Gutwein P, Mechtersheimer S, Riedle S, Stoeck A, Gast D, Joumaa S, Zentgraf H, Fogel M, Altevogt DP (February 2003). "ADAM10-mediated cleavage of L1 adhesion molecule at the cell surface and in released membrane vesicles". FASEB Journal. 17 (2): 292–4. doi:10.1096/fj.02-0430fje. PMID 12475894.
and 6 Related for: ADAM10 endopeptidase information
ADAM10endopeptidase (EC 3.4.24.81, Kuzbanian protein, myelin-associated disintegrin metalloproteinase) is an enzyme. This enzyme catalyses the following...
domain-containing protein 10, also known as ADAM10 or CDw156 or CD156c is a protein that in humans is encoded by the ADAM10 gene. Members of the ADAM family are...
activated leukocyte cell adhesion molecule as substrates of ADAM17 and ADAM10 by difference gel electrophoresis. Mol. Cell Biol. 26(13):5086-95 (2006)...
Guardiola-Serrano F, et al. (2007). "The Fas ligand intracellular domain is released by ADAM10 and SPPL2a cleavage in T-cells". Cell Death Differ. 14 (9): 1678–87. doi:10...
metalloproteinases (MMPs) are a large multigene family of zinc-dependent endopeptidases. The collective MMP family is capable of degrading all known ECM macromolecules...
breast cancer cells, Paxillin phosphorylation at S272 and S274 activates ADAM10 protease, and STAT5 phosphorylation at S779 modulates BCL-ABL-mediated leukemogenesis...