60S ribosomal protein L30 information

RPL30
Available structures
PDB	Ortholog search: PDBe RCSB
List of PDB id codes
	3VI6, 4UG0, 4V6X, 5AJ0, 3J92, 4UJC, 3J7P, 4UJE, 3J7Q, 3J7R, 4D67, 4UJD, 4V5Z, 4D5Y, 3J7O
Identifiers
Aliases	RPL30, L30, ribosomal protein L30
External IDs	OMIM: 180467; MGI: 98037; HomoloGene: 766; GeneCards: RPL30; OMA:RPL30 - orthologs
Gene location (Human)
Chr.	Chromosome 8 (human)
End	98,046,469 bp
Gene location (Mouse)
Chr.	Chromosome 15 (mouse)
End	34,443,786 bp
RNA expression pattern
	Top expressed in
	parietal pleura; ; urethra; ; skin of hip; ; germinal epithelium; ; left ovary; ; skin of thigh; ; secondary oocyte; ; lactiferous duct; ; right ovary; ; caput epididymis;
	Top expressed in
	ventricular zone; ; yolk sac; ; neural layer of retina; ; embryo; ; embryo; ; lip; ; morula; ; blastocyst; ; dentate gyrus of hippocampal formation granule cell; ; muscle of thigh;
	More reference expression data
	More reference expression data
Gene ontology
Molecular function	structural constituent of ribosome; protein binding; RNA binding; selenocysteine insertion sequence binding;
Cellular component	cytosol; ribosome; membrane; focal adhesion; intracellular anatomical structure; extracellular exosome; nucleus; extracellular matrix; cytosolic large ribosomal subunit; postsynaptic density; polysomal ribosome;
Biological process	protein biosynthesis; viral transcription; SRP-dependent cotranslational protein targeting to membrane; translational initiation; nuclear-transcribed mRNA catabolic process, nonsense-mediated decay; rRNA processing; antimicrobial humoral immune response mediated by antimicrobial peptide; cytoplasmic translation; liver regeneration; positive regulation of selenocysteine incorporation;
	Sources:Amigo / QuickGO
Orthologs
	6156
	19946
	ENSG00000156482
	ENSMUSG00000058600
	P62888
	P62889
	NM_000989
	NM_001163485; NM_009083
	NP_000980
	NP_001156957; NP_033109
	Wikidata
View/Edit Human	View/Edit Mouse

60S ribosomal protein L30 is a protein that in humans is encoded by the RPL30 gene.^[5]^[6]

Ribosomes, the organelles that catalyze protein synthesis, consist of a small 40S subunit and a large 60S subunit. Together these subunits are composed of 4 RNA species and approximately 80 structurally distinct proteins. This gene encodes a ribosomal protein that is a component of the 60S subunit. The protein belongs to the L30E family of ribosomal proteins. It is located in the cytoplasm. This gene is co-transcribed with the U72 small nucleolar RNA gene, which is located in its fourth intron. As is typical for genes encoding ribosomal proteins, there are multiple processed pseudogenes of this gene dispersed through the genome.^[6]

^ ^a ^b ^c GRCh38: Ensembl release 89: ENSG00000156482 – Ensembl, May 2017
^ ^a ^b ^c GRCm38: Ensembl release 89: ENSMUSG00000058600 – Ensembl, May 2017
^ "Human PubMed Reference:". National Center for Biotechnology Information, U.S. National Library of Medicine.
^ "Mouse PubMed Reference:". National Center for Biotechnology Information, U.S. National Library of Medicine.
^ Feo S, Davies B, Fried M (Jun 1992). "The mapping of seven intron-containing ribosomal protein genes shows they are unlinked in the human genome". Genomics. 13 (1): 201–207. doi:10.1016/0888-7543(92)90221-D. PMID 1577483.
^ ^a ^b "Entrez Gene: RPL30 ribosomal protein L30".

[refGRCh38Ensembl-1] GRCh38: Ensembl release 89: ENSG00000156482 – Ensembl, May 2017

[refGRCm38Ensembl-2] GRCm38: Ensembl release 89: ENSMUSG00000058600 – Ensembl, May 2017

[3] "Human PubMed Reference:". National Center for Biotechnology Information, U.S. National Library of Medicine.

[4] "Mouse PubMed Reference:". National Center for Biotechnology Information, U.S. National Library of Medicine.

[pmid1577483-5] Feo S, Davies B, Fried M (Jun 1992). "The mapping of seven intron-containing ribosomal protein genes shows they are unlinked in the human genome". Genomics. 13 (1): 201–207. doi:10.1016/0888-7543(92)90221-D. PMID 1577483.

[entrez-6] "Entrez Gene: RPL30 ribosomal protein L30".

60S ribosomal protein L30 information

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