40S ribosomal protein S27 information

RPS27
Available structures
PDB	Ortholog search: PDBe RCSB
List of PDB id codes
	4UG0, 4V6X, 5A2Q, 5AJ0, 4KZY, 3J7R, 4D61, 4KZX, 4D5L, 5FLX, 4UJD, 3J7P, 4KZZ, 4UJE, 4UJC
Identifiers
Aliases	RPS27, MPS-1, MPS1, S27, ribosomal protein S27, DBA17
External IDs	OMIM: 603702; MGI: 1915191; HomoloGene: 803; GeneCards: RPS27; OMA:RPS27 - orthologs
Gene location (Human)
Chr.	Chromosome 1 (human)
End	153,992,155 bp
Gene location (Mouse)
Chr.	Chromosome 9 (mouse)
End	66,856,798 bp
RNA expression pattern
	Top expressed in
	ganglionic eminence; ; granulocyte; ; left ovary; ; right ovary; ; canal of the cervix; ; lymph node; ; Achilles tendon; ; ventricular zone; ; uterine tube; ; corpus callosum;
	Top expressed in
	embryo; ; endocardial cushion; ; embryo; ; parotid gland; ; right kidney; ; seminal vesicula; ; lacrimal gland; ; epiblast; ; yolk sac; ; zygote;
	More reference expression data
	More reference expression data
Gene ontology
Molecular function	DNA binding; structural constituent of ribosome; zinc ion binding; metal ion binding; protein binding; RNA binding;
Cellular component	cytosol; ribosome; intracellular anatomical structure; nucleus; nucleoplasm; cytosolic small ribosomal subunit; postsynaptic density; presynapse; glutamatergic synapse; GABA-ergic synapse;
Biological process	viral transcription; SRP-dependent cotranslational protein targeting to membrane; translational initiation; ribosomal small subunit assembly; nuclear-transcribed mRNA catabolic process, nonsense-mediated decay; cell population proliferation; protein biosynthesis; sister chromatid cohesion; rRNA processing;
	Sources:Amigo / QuickGO
Orthologs
	6232
	67941
	ENSG00000177954
	ENSMUSG00000036781
	P42677
	Q6ZWY3
	NM_001030; NM_001349946; NM_001349947
	NM_026467; NM_001311101; NM_001361106
	NP_001021; NP_001336875; NP_001336876
	NP_001298030; NP_080743; NP_001348035
	Wikidata
View/Edit Human	View/Edit Mouse

40S ribosomal protein S27, also known as metallopan-stimulin 1 or MPS-1, is a protein that in humans is encoded by the RPS27 gene.^[5]^[6]^[7] Metallopanstimulin is a zinc finger protein proposed to be involved DNA repair as well as oncogenesis.^[8]

^ ^a ^b ^c GRCh38: Ensembl release 89: ENSG00000177954 – Ensembl, May 2017
^ ^a ^b ^c GRCm38: Ensembl release 89: ENSMUSG00000036781 – Ensembl, May 2017
^ "Human PubMed Reference:". National Center for Biotechnology Information, U.S. National Library of Medicine.
^ "Mouse PubMed Reference:". National Center for Biotechnology Information, U.S. National Library of Medicine.
^ Tsui SK, Lee SM, Fung KP, Waye MM, Lee CY (Oct 1996). "Primary structures and sequence analysis of human ribosomal proteins L39 and S27". Biochemistry and Molecular Biology International. 40 (3): 611–6. doi:10.1080/15216549600201203. PMID 8908372. S2CID 7909023.
^ Fernandez-Pol JA, Klos DJ, Hamilton PD (Oct 1993). "A growth factor-inducible gene encodes a novel nuclear protein with zinc finger structure". The Journal of Biological Chemistry. 268 (28): 21198–204. doi:10.1016/S0021-9258(19)36910-8. PMID 8407955.
^ "Entrez Gene: RPS27 ribosomal protein S27 (metallopanstimulin 1)".
^ Fernandez-Pol JA (1996). "Metallopanstimulin as a novel tumor marker in sera of patients with various types of common cancers: implications for prevention and therapy". Anticancer Research. 16 (4B): 2177–85. PMID 8694540.

[refGRCh38Ensembl-1] GRCh38: Ensembl release 89: ENSG00000177954 – Ensembl, May 2017

[refGRCm38Ensembl-2] GRCm38: Ensembl release 89: ENSMUSG00000036781 – Ensembl, May 2017

[3] "Human PubMed Reference:". National Center for Biotechnology Information, U.S. National Library of Medicine.

[4] "Mouse PubMed Reference:". National Center for Biotechnology Information, U.S. National Library of Medicine.

[pmid8908372-5] Tsui SK, Lee SM, Fung KP, Waye MM, Lee CY (Oct 1996). "Primary structures and sequence analysis of human ribosomal proteins L39 and S27". Biochemistry and Molecular Biology International. 40 (3): 611–6. doi:10.1080/15216549600201203. PMID 8908372. S2CID 7909023.

[pmid8407955-6] Fernandez-Pol JA, Klos DJ, Hamilton PD (Oct 1993). "A growth factor-inducible gene encodes a novel nuclear protein with zinc finger structure". The Journal of Biological Chemistry. 268 (28): 21198–204. doi:10.1016/S0021-9258(19)36910-8. PMID 8407955.

[entrez-7] "Entrez Gene: RPS27 ribosomal protein S27 (metallopanstimulin 1)".

[Fernandez-Pol_1996-8] Fernandez-Pol JA (1996). "Metallopanstimulin as a novel tumor marker in sera of patients with various types of common cancers: implications for prevention and therapy". Anticancer Research. 16 (4B): 2177–85. PMID 8694540.

40S ribosomal protein S27 information

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40S ribosomal protein S27

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S27

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RPS27L