The 2010 United States Senate election in Oregon was held on November 2, 2010 alongside other elections to the United States Senate in other states, as well as elections to the United States House of Representatives and various state and local elections. Incumbent Democratic U.S. Senator Ron Wyden won re-election to a third full term by a landslide margin of 18 points, despite the national Republican midterm wave. As of 2022, this is the only senate election since 1998 in which Deschutes County has not supported the Democratic candidate (albeit by a plurality).
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