An artificially colored transmission electron micrograph of the Reston virus
Virus classification
(unranked):
Virus
Realm:
Riboviria
Kingdom:
Orthornavirae
Phylum:
Negarnaviricota
Class:
Monjiviricetes
Order:
Mononegavirales
Family:
Filoviridae
Genus:
Ebolavirus
Species:
Reston ebolavirus
Synonyms
Reston virus (RESTV)
Reston virus (RESTV) is one of six known viruses within the genus Ebolavirus. Reston virus causes Ebola virus disease in non-human primates; unlike the other five ebolaviruses, it is not known to cause disease in humans, but has caused asymptomatic infections.[1][2][3] Reston virus was first described in 1990 as a new "strain" of Ebola virus (EBOV).[4] It is the single member of the species Reston ebolavirus, which is included into the genus Ebolavirus, family Filoviridae, order Mononegavirales.[5] Reston virus is named after Reston, Virginia, US, where the virus was first discovered.
RESTV was discovered in crab-eating macaques from Hazleton Laboratories (now Labcorp Drug Development) in 1989. This attracted significant media attention due to Reston's location in the Washington metropolitan area and the lethality of a closely related Ebola virus. Despite its status as a level-4 organism, Reston virus is non-pathogenic to humans, though hazardous to monkeys;[6][7] the perception of its lethality was compounded by the monkey's coinfection with Simian hemorrhagic fever virus (SHFV).[8] Despite ongoing research, the determinants for lack of human pathogenicity are yet to be discovered.[9]
^Spickler, Anna. "Ebolavirus and Marburgvirus Infections" (PDF).
^"About Ebola Virus Disease". CDC. Retrieved 18 October 2014.
^"Years of Ebola Virus Disease Outbreaks | 2014-2016 Outbreak West Africa | History | Ebola (Ebola Virus Disease) | CDC". 2018-11-09.
^Geisbert, T. W.; Jahrling, P. B. (1990). "Use of immunoelectron microscopy to show Ebola virus during the 1989 United States epizootic". Journal of Clinical Pathology. 43 (10): 813–816. doi:10.1136/jcp.43.10.813. PMC 502829. PMID 2229429.
^Kuhn, Jens H.; Becker, Stephan; Ebihara, Hideki; Geisbert, Thomas W.; Johnson, Karl M.; Kawaoka, Yoshihiro; Lipkin, W. Ian; Negredo, Ana I; et al. (2010). "Proposal for a revised taxonomy of the family Filoviridae: Classification, names of taxa and viruses, and virus abbreviations". Archives of Virology. 155 (12): 2083–103. doi:10.1007/s00705-010-0814-x. PMC 3074192. PMID 21046175.
^Special Pathogens Branch CDC (2008-01-14). "Known Cases and Outbreaks of Ebola Hemorrhagic Fever". Centers for Disease Control and Prevention. Archived from the original on 2008-08-29. Retrieved 2008-08-02.
^McCormick & Fisher-Hoch 1999, p. 300
^McCormick & Fisher-Hoch 1999, pp. 307–309
^Cantoni, Diego (December 28, 2016). "Risks Posed by Reston, the Forgotten Ebolavirus". mSphere. 1 (6). doi:10.1128/mSphere.00322-16. PMC 5196033. PMID 28066813.
Restonvirus (RESTV) is one of six known viruses within the genus Ebolavirus. Restonvirus causes Ebola virus disease in non-human primates; unlike the...
diseases, Ebola virus disease and Marburg virus disease, Preston described a 1989 incident in which a relative of Ebola virus, Restonvirus, was discovered...
the largest number of outbreaks. The fifth and sixth viruses, Restonvirus (RESTV) and Bombali virus (BOMV), are not thought to cause disease in humans...
member virus, and four of these cause Ebola virus disease (EVD) in humans, a type of hemorrhagic fever having a very high case fatality rate. The Reston virus...
Committee on Taxonomy of Viruses: Ebola virus (EBOV), Sudan virus (SUDV), Restonvirus (RESTV), Taï Forest virus (TAFV), and Bundibugyo virus (BDBV). Four of the...
the four species included in the analysis (Ebola virus, Tai Forest virus, Sudan virus, and Restonvirus) estimated at 1000–2100 years. The most recent common...
Prentice Hall Restonvirus, a form of Ebolavirus Reston Parkway (disambiguation) Reston Station, a mixed-use development and railway station in Reston, Virginia...
have been reported to be infected with Restonvirus, so other interim or amplifying hosts may exist. Ebola virus outbreaks tend to occur when temperatures...
"Monkey ebola virus likely not harmful to humans", San Antonio Express News, April 17, 1996. Rollin, Pierre E. et al. "Ebola (Subtype Reston) Virus among Quarantined...
two Marburgviruses: Marburg virus (MARV) and Ravn virus (RAVV). Its clinical symptoms are very similar to those of Ebola virus disease (EVD). Egyptian fruit...
second filovirus that is not pathogenic for humans (the first one being Restonvirus (RESTV)).[citation needed] Seroreactivity of additional Schreibers's...
Marburg virus (MARV) is a hemorrhagic fever virus of the Filoviridae family of viruses and a member of the species Marburg marburgvirus, genus Marburgvirus...
for his research into Ebola and AIDS. After helping discover the Ebola virus in 1976 and leading efforts to contain the first-ever recorded Ebola epidemic...
2018. Their next project, The Hot Zone, tells the true story of the Restonvirus in the US in 1989. It will be released on National Geographic on Memorial...
The 2013–2016 epidemic of Ebola virus disease, centered in Western Africa, was the most widespread outbreak of the disease in history. It caused major...
Four laboratory-confirmed cases of Ebola virus disease (commonly known as "Ebola") occurred in the United States in 2014. Eleven cases were reported,...
different from Ebola virus by ≥30% but different from that of Sudan virus by <30% Sudan virus (SUDV) is one of six known viruses within the genus Ebolavirus...
The 1967 Marburg virus outbreak was the first recorded outbreak of Marburg virus disease. It started in early August 1967 when 30 people became ill in...
surgeon who played a major role in stemming a 1976 outbreak of the Ebola virus in Zaire, the first major outbreak of the viral hemorrhagic fever in Central...
An Ebola virus epidemic in Sierra Leone occurred in 2014, along with the neighbouring countries of Guinea and Liberia. At the time it was discovered,...
virus, human respiratory syncytial virus, measles virus, mumps virus, Nipah virus, and rabies virus. Important pathogens of nonhuman animals and plants...
An epidemic of Ebola virus disease in Guinea from 2013 to 2016 represents the first ever outbreak of Ebola in a West African country. Previous outbreaks...
Ebola virus disease occurred in Liberia from 2014 to 2015, along with the neighbouring countries of Guinea and Sierra Leone. The first cases of virus were...
outbreak of Ebola infections among monkeys imported to Reston (Virginia) in 1990 (→ Restonvirus); and Epidemiological and diagnostic support to the World...