Percutaneous hepatic perfusion (PHP) is a regionalized, minimally-invasive approach to cancer treatment[1] currently undergoing Phase II and Phase III clinical testing. PHP treats a variety of hepatic tumors by isolating the liver and exposing the organ to high-dose chemotherapy. As demonstrated in clinical trials, patients treated by PHP can tolerate much higher doses of chemotherapeutic agents than those receiving traditional systemic chemotherapy without increased toxicities.[citation needed]
^Morita, Shane Y.; Balch, Charles M.; Klimberg, V. Suzanne; Pawlik, Timothy M.; Posner, Glenn David; Tanabe, Kenneth K. (2017). Textbook of General Surgical Oncology. McGraw Hill Professional. p. 169. ISBN 9780071793322. Retrieved 11 July 2019.
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Percutaneoushepaticperfusion (PHP) is a regionalized, minimally-invasive approach to cancer treatment currently undergoing Phase II and Phase III clinical...
property portfolio consisting of 28 patents worldwide. Delcath's PercutaneousHepaticPerfusion (PHP) is currently undergoing Phase II and Phase III trials...
percutaneous drainage, or sometimes re-operation. Vascular complications include thrombosis, stenosis, pseudoaneurysm, and rupture of the hepatic artery...
scans are performed with intravenous contrast in multiple phases of hepaticperfusion to improve detection and accurate classification of any liver lesions...
et al. (December 2012). "Chemosaturation with PercutaneousHepaticPerfusion for Unresectable Isolated Hepatic Metastases from Sarcoma". CardioVascular and...
sample from the area of interest for pathological examination from a percutaneous or transvenous approach. Vascular Balloon angioplasty/stent: Opening...
is the tissue damage caused when blood supply returns to tissue (re- + perfusion) after a period of ischemia or lack of oxygen (anoxia or hypoxia). The...
de Wilt JH, ten Hagen TL, Eggermont AM (October 2008). "Isolated hepaticperfusion for the treatment of liver tumors: sunset or sunrise?". Surgical Oncology...
centre frequency of the transmitted ultrasound. Harmonic imaging used for perfusion detection when using ultrasound contrast agents and for the detection...
for limb loss, such as wound and infection severity. Angioplasty (or percutaneous transluminal angioplasty) can be done on solitary lesions in large arteries...
the narrowing of the arteries supplying the kidneys which causes a low perfusion pressure that is detected by the juxtaglomerular apparatus (via the macula...
increases the time they remain viable for transplant. Although chilling and perfusion may extend intestinal lifespans by several hours, failure is still imminent...