Immune Epitope Database and Analysis Resource information
Project hosted by scientists at the La Jolla Institute for Allergy and Immunology
The Immune Epitope Database and Analysis Resource (IEDB) is a project hosted by scientists at the La Jolla Institute for Allergy and Immunology (LIAI), with support from the National Institute of Allergy and Infectious Diseases (NIAID), a part of the National Institutes of Health[permanent dead link] (NIH), and Department of Health and Human Services (HHS). The focus is dissemination of immune epitope information to facilitate the generation of new research tools, diagnostic techniques, vaccines and therapeutics.
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Relevant Databases". InnateDB. ImmuneEpitopeDatabaseandAnalysisResource. National Institutes of Health in the Department of Health and Human Services...
activation and consequent decline in self-tolerance. Epitope spreading or epitope drift – when the immune reaction changes from targeting the primary epitope to...
1093/nar/gkl849. PMC 1669746. PMID 17090587. Sette, A. et al. The immuneepitopedatabaseandanalysisresource. Pattern Recognition in Bioinformatics, Proceedings...
Virus Pathogen DatabaseandAnalysisResource (ViPR) is an integrative and comprehensive publicly available databaseandanalysisresource to search, analyze...
Research Database (IRD) is an integrative and comprehensive publicly available databaseandanalysisresource to search, analyze, visualize, save and share...
the body's own epitopes; many can be detected through blood tests. Antibodies directed against red blood cell surface antigens in immune mediated hemolytic...
work in databases like the ImmuneEpitopeDatabaseandAnalysisResource. Biocurators usually are PhD-level with a mix of experiences in wet lab and computational...
president and scientific director. That same year, the ImmuneEpitopeDatabase (IEDB) was established and launched. The database was designed and developed...
experimental, clinical, and translational neuroscience databases, knowledge bases, atlases, and genetic/genomic resources and provides many authoritative...
presentation often varies between age groups andimmune status. Reinfection is common throughout life, but infants and the elderly remain at risk for symptomatic...
(2014). "Survey of Epstein Barr Virus (EBV) Immunogenic Proteins and their Epitopes: Implications for Vaccine Preparation". Recent Patents on Anti-Infective...
"escape mutation" as the viral epitopes escape recognition by the host immune response. These persistent viruses evade immune control by sequestration, blockade...
proteomics studies, published immune assay data and a longitudinal study based on proximity extension assay (PEA). Further, an analysis of the “human secretome”...
Alphavirus Virus Pathogen DatabaseandAnalysisResource (ViPR): Togaviridae This article incorporates text from the public domain Pfam and InterPro: IPR000936...
Jennifer G. (2018). "The role of mass spectrometry and proteogenomics in the advancement of HLA epitope prediction". Proteomics. 18 (12): e1700259. doi:10...
carbohydrates and genetic predisposition involving HLA Class II genes that trigger autoimmune reactions. Molecular mimicry occurs when epitopes are shared...
allotypes that recognize the C2 epitope of HLA-C are common among Africans and absent from Europeans". Immunity, Inflammation and Disease. 5 (4): 461–468. doi:10...
is a certain degree of homology between the rickettsiae and the virus, namely, common epitope(s) due to common genome fragment(s) in both pathogens. Surprisingly...
The vaccines require two or three doses depending on a person's age andimmune status. Vaccinating girls around the ages of nine to thirteen is typically...
the human immune system. These sites are referred to as epitope sites. Phylogenetic analysis of H3N2 influenza has shown that putative epitope sites of...
engineering T cells. T cell receptors were engineered and 'trained' to detect cancer epitopes. Chimeric antigen receptors (CARs) are composed of a fragment...
viral infection, NS4B can trigger humoral and cellular immune responses thanks to its highly conserved epitopes. NS5B (p75), which features a functional...
size of the micropeptide can also lead to difficulties in designing an epitope from which to target the antibody. Genome editing can be used to add FLAG/MYC...
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