Diffuse myelinoclastic sclerosis, sometimes referred to as Schilder's disease, is a very infrequent neurodegenerative disease that presents clinically as pseudotumoural demyelinating lesions, making its diagnosis difficult. It usually begins in childhood, affecting children between 5 and 14 years old,[1][2] but cases in adults are also possible.[3]
This disease is considered one of the borderline forms of multiple sclerosis because some authors consider them different diseases and others MS variants. Other diseases in this group are neuromyelitis optica (NMO), Balo concentric sclerosis and Marburg multiple sclerosis.[4]
^Garrido C, Levy-Gomes A, Teixeira J, Temudo T (2004). "[Schilder's disease: two new cases and a review of the literature]". Revista de Neurología (in Spanish). 39 (8): 734–8. doi:10.33588/rn.3908.2003023. PMID 15514902.
^Afifi AK, Bell WE, Menezes AH, Moore SA (1994). "Myelinoclastic diffuse sclerosis (Schilder's disease): report of a case and review of the literature". J. Child Neurol. 9 (4): 398–403. CiteSeerX 10.1.1.1007.559. doi:10.1177/088307389400900412. PMID 7822732. S2CID 38765870.
Diffusemyelinoclasticsclerosis, sometimes referred to as Schilder's disease, is a very infrequent neurodegenerative disease that presents clinically...
disease' can refer to a rare variant of multiple sclerosis also known as diffusemyelinoclasticsclerosis). Schilder was the son of a Jewish silk merchant...
PMID 15514902. Afifi AK, Bell WE, Menezes AH, Moore SA (1994). "Myelinoclasticdiffusesclerosis (Schilder's disease): report of a case and review of the literature"...
and combining the characteristics of Addison's disease and diffusemyelinoclasticsclerosis (Schilder's disease). Females are not affected by the condition...
can sometimes get better spontaneously. Schilder disease or diffusemyelinoclasticsclerosis: is a rare disease that presents clinically as a pseudotumoural...
adrenoleukodystrophy, myelinoclasticdiffusesclerosis... The eponymic designation should be reserved for instances of myelinoclasticdiffusesclerosis that correspond...