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Carol Jennings information


Carol Jennings
Born
Carol Joyce Bexon

(1954-03-25)25 March 1954
Nottingham, England
Died29 March 2024(2024-03-29) (aged 70)
Coventry, England
NationalityBritish
Years active1986–2024
Known forAlzheimer's Disease activism

Carol Joyce Jennings (née Bexon; 25 March 1954 – 29 March 2024) was a British campaigner and advocate for research into Alzheimer's Disease. She served as an honorary Vice-President of the Alzheimer's Society until her death in 2024.[1] Through her activism in the 1980s, Jennings brought her family to the attention of researchers studying the disease, which subsequently led to the discovery of the London Mutation.[2][3] This mutation, found on the Amyloid Precursor Protein (APP) gene located on chromosome 21, marked a significant breakthrough in understanding the genetic basis of Alzheimer's Disease[1] and provided evidence for the development of the 'amyloid hypothesis', which attempts to explain the underlying causes of Alzheimer's Disease.[1][4]

  1. ^ a b c "Honouring a couple affected by dementia for their contributions to dementia research". Alzheimer's Society. Retrieved 12 September 2023.
  2. ^ "APP V717I (London)". Alzheimer Research Forum. Retrieved 12 September 2023.
  3. ^ HIH.gov Archived 5 November 2011 at the Wayback Machine
  4. ^ "Feature: The 'historic' Alzheimer's breakthrough that is 30 years in the making". University College London. 2 December 2022. Retrieved 12 September 2023.

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