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COS cells information


COS-7 cells, 40X magnification

COS are fibroblast-like cell lines derived from monkey kidney tissue. COS cells are obtained by immortalizing CV-1 cells[1] with a version of the SV40 virus that can produce large T antigen but has a defect in genomic replication.[2] The CV-1 cell line in turn was derived from the kidney of the African green monkey.[3]

The acronym "COS" is derived from the cells being CV-1 (simian) in Origin, and carrying the SV40 genetic material.[2] Three COS lines were created (COS-1, COS-3 and COS-7), of which two are commonly used (COS-1 and COS-7).

  1. ^ Jensen FC, Girardi AJ, Gilden RV, Koprowski H (July 1964). "Infection of human and simian tissue cultures with rous sarcoma virus". Proc. Natl. Acad. Sci. U.S.A. 52 (1): 53–9. Bibcode:1964PNAS...52...53J. doi:10.1073/pnas.52.1.53. PMC 300571. PMID 14192657.
  2. ^ a b Gluzman Y (January 1981). "SV40-transformed simian cells support the replication of early SV40 mutants". Cell. 23 (1): 175–82. doi:10.1016/0092-8674(81)90282-8. PMID 6260373. S2CID 36241020.
  3. ^ Fanelli, Alex (2016). "COS-7 cell line: Origin and Characteristics". Retrieved 28 November 2017.

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COS cells

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COS are fibroblast-like cell lines derived from monkey kidney tissue. COS cells are obtained by immortalizing CV-1 cells with a version of the SV40 virus...

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Cos

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Look up Cos or cos in Wiktionary, the free dictionary. Cos, COS, CoS, coS or Cos. may refer to: Carbonyl sulfide Class of service (CoS or COS), a network...

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Crystal structure

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cos ⁡ α ) + 2 h ℓ a c ( cos ⁡ γ cos ⁡ α − cos ⁡ β ) + 2 h k a b ( cos ⁡ α cos ⁡ β − cos ⁡ γ ) 1 − cos 2 ⁡ α − cos 2 ⁡ β − cos 2 ⁡ γ + 2 cos ⁡ α cos ⁡...

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Cosmid

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resistance, so that the transformed cells can be identified by plating on a medium containing the antibiotic. Those cells which did not take up the cosmid...

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Fourier series

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( y ) = a 0 cos ⁡ π y 2 + a 1 cos ⁡ 3 π y 2 + a 2 cos ⁡ 5 π y 2 + ⋯ . {\displaystyle \varphi (y)=a_{0}\cos {\frac {\pi y}{2}}+a_{1}\cos 3{\frac {\pi...

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Kerr effect

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2022-01-22. Kerr cells in early television Archived 2016-10-01 at the Wayback Machine (Scroll down the page for several early articles on Kerr cells.)...

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Klein bottle

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3 cos 2 ⁡ u cos ⁡ v − 48 cos 4 ⁡ u cos ⁡ v + 48 cos 6 ⁡ u cos ⁡ v − 60 sin ⁡ u + 5 cos ⁡ u cos ⁡ v sin ⁡ u − 5 cos 3 ⁡ u cos ⁡ v sin ⁡ u − 80 cos 5 ⁡...

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P53

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into stem cells with a much greater efficiency than normal cells. Papers suggest that the lack of cell cycle arrest and apoptosis gives more cells the chance...

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Enteropeptidase

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reduction of the natural protein or by mutagenesis and expression in COS cells. Native enteropeptidase and the isolated light chain have similar activity...

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Rhombohedron

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( 1 − cos ⁡ θ ) 1 + 2 cos ⁡ θ = a 3 ( 1 − cos ⁡ θ ) 2 ( 1 + 2 cos ⁡ θ ) = a 3 1 − 3 cos 2 ⁡ θ + 2 cos 3 ⁡ θ   . {\displaystyle V=a^{3}(1-\cos \theta...

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Structure and genome of HIV

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lines. It does not appear to require Vif for the same process in HeLa cells or COS cells, among others. nef- Nef, negative factor, is a N-terminal myristoylated...

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Lattice constant

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unit cell V = a b c 1 + 2 cos ⁡ α cos ⁡ β cos ⁡ γ − cos 2 ⁡ α − cos 2 ⁡ β − cos 2 ⁡ γ . {\displaystyle V=abc{\sqrt {1+2\cos \alpha \cos \beta \cos \gamma...

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GABA receptor

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rho 1 and GABA alpha/beta receptors expressed in Xenopus oocytes and COS cells". Br. J. Pharmacol. 109 (1): 200–6. doi:10.1111/j.1476-5381.1993.tb13554...

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Cell culture

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cells is genetically determined, but some cell-culturing cells have been 'transformed' into immortal cells which will reproduce indefinitely if the optimal...

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Bravais lattice

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multiple of a unit cell.) There are mainly two types of unit cells: primitive unit cells and conventional unit cells. A primitive cell is the very smallest...

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White Blood Cells

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and Roll Hall of Fame added White Blood Cells to their 200 Definitive Albums list. In 2012, White Blood Cells appeared on Rolling Stone's "The 500 Greatest...

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Tetrahedron

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1 cos ⁡ ( α 12 ) cos ⁡ ( α 13 ) cos ⁡ ( α 14 ) cos ⁡ ( α 12 ) − 1 cos ⁡ ( α 23 ) cos ⁡ ( α 24 ) cos ⁡ ( α 13 ) cos ⁡ ( α 23 ) − 1 cos ⁡ ( α 34 ) cos ⁡...

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Hadley cell

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air called meridional cells. These include the prominent "Hadley cells" centered over the tropics and the weaker "Ferrell cells" centered over the mid-latitudes...

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Soft Cell

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Show on BBC Radio 2 that Soft Cell were releasing two new tracks ahead of the concert: "Northern Lights" and "Guilty (Cos I Say You Are)". Entitled "Say...

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Gabor filter

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= x cos ⁡ θ + y sin ⁡ θ {\displaystyle x'=x\cos \theta +y\sin \theta } and y ′ = − x sin ⁡ θ + y cos ⁡ θ {\displaystyle y'=-x\sin \theta +y\cos \theta...

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Hough transform

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and P 0 = ( r cos ⁡ θ , r sin ⁡ θ ) {\displaystyle P_{0}=(r\cos \theta ,r\sin \theta )} , we get r ( x cos ⁡ θ + y sin ⁡ θ ) = r 2 ( cos 2 ⁡ θ + sin 2...

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4D printing

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cos ⁡ ( 2 θ ) + m 4 cos ⁡ ( 4 θ ) {\displaystyle H=c_{1}{\frac {\alpha _{\parallel }-\alpha _{\perp }}{h}}{\frac {\sin ^{2}(\theta )}{c_{2}-c_{3}\cos(2\theta...

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Transmitarray antenna

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Transmitarrays consist of an array of unit cells placed above a source (feeding) antenna. Phase shifts are applied to the unit cells, between elements on the receive...

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Heterodyne

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cos ⁡ θ 1 ) ( cos ⁡ θ 2 ) = 1 2 cos ⁡ ( θ 1 − θ 2 ) + 1 2 cos ⁡ ( θ 1 + θ 2 ) {\displaystyle (\cos \theta _{1})(\cos \theta _{2})={\tfrac {1}{2}}\cos(\theta...

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