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Benzphetamine information


Benzphetamine
Benzphetamine.svg
Benzphetamine 3d.gif
Clinical data
Trade namesDidrex, Recede
Other namesN-benzyl-N-methylamphetamine
AHFS/Drugs.comProfessional Drug Facts
License data
  • US DailyMed: Benzphetamine
Dependence
liability
High[1]
Routes of
administration
By mouth
ATC code
  • None
Legal status
Legal status
  • AU: S4 (Prescription only)
  • CA: Schedule I
  • DE: Anlage I (Authorized scientific use only)
  • UK: Class C
  • US: Schedule III
Pharmacokinetic data
Protein binding75–99%
Elimination half-life4-6 hours
Identifiers
IUPAC name
  • (2S)-N-Benzyl-N-methyl-1-phenylpropan-2-amine
CAS Number
  • 156-08-1 checkY
PubChem CID
  • 5311017
DrugBank
  • DB00865 checkY
ChemSpider
  • 4470556 checkY
UNII
  • 0M3S43XK27
KEGG
  • D07514
  • D07515
ChEBI
  • CHEBI:3044 checkY
ChEMBL
  • ChEMBL3545985 ☒N
CompTox Dashboard (EPA)
  • DTXSID4022656 Edit this at Wikidata
Chemical and physical data
FormulaC17H21N
Molar mass239.362 g·mol−1
3D model (JSmol)
  • Interactive image
SMILES
  • N(C)(Cc1ccccc1)[C@@H](C)Cc2ccccc2
InChI
  • InChI=1S/C17H21N/c1-15(13-16-9-5-3-6-10-16)18(2)14-17-11-7-4-8-12-17/h3-12,15H,13-14H2,1-2H3/t15-/m0/s1 checkY
  • Key:YXKTVDFXDRQTKV-HNNXBMFYSA-N checkY
 ☒NcheckY (what is this?)  (verify)

Benzphetamine (brand name Didrex) is a substituted amphetamine used short-term along with a doctor-approved, reduced-calorie diet, exercise, and behavioral program for weight loss. It is prescribed for obesity to people who have been unable to lose weight through exercise and dieting alone. It is a prodrug to dextroamphetamine and dextromethamphetamine.[2][3][4]

Benzphetamine is an anorectic, primarily promoting weight loss through reduced appetite. It also slightly increases metabolism.

  1. ^ "Benzphetamine". Toxnet. Archived from the original on 2018-11-01.
  2. ^ AHC Media, LLC (17 March 2014). Pediatric Trauma Care II: A clinical reference for physicians and nurses caring for the acutely injured child. AHC Media, LLC. pp. 118–. ISBN 978-1-934863-59-6.
  3. ^ Cody JT, Valtier S (1998). "Detection of amphetamine and methamphetamine following administration of benzphetamine". Journal of Analytical Toxicology. 22 (4): 299–309. doi:10.1093/jat/22.4.299. PMID 9681333.
  4. ^ Budd RD, Jain NC (1978). "Short Communication: Metabolism and Excretion of Benzphetamine: Sources of Error in Reporting Results". Journal of Analytical Toxicology. 2 (6): 241. doi:10.1093/jat/2.6.241.

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